Two Targets, One Hit: new Anticancer Therapeutics to Prevent Tumorigenesis Without Cardiotoxicity
نویسندگان
چکیده
A serious adverse effect of cancer therapies is cardiovascular toxicity, which significantly limits the widespread use antineoplastic agents. The promising new field cardio-oncology offers identification potent anti-cancer therapeutics that effectively inhibit cell proliferation without causing cardiotoxicity. Future introduction recently identified cardio-safe compounds into clinical practice (including ERK dimerization inhibitors or BAX allosteric inhibitors) expected to help oncologists avoid unwanted cardiological complications associated with therapeutic interventions.
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: ['1663-9812']
DOI: https://doi.org/10.3389/fphar.2020.569955